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Cyclophosphamide tablets usp 50 mg is successful alone in vulnerable malignancies, are all the more as often as possible utilized simultaneously or consecutively with other antineoplastic drugs. It is utilized as a part of treatment of malignant lymphomas (stages iii and iv of the ann arbor arranging framework), hodgkin's sickness, lymphocytic lymphoma (nodular or diffuse), blended cell write lymphoma, histiocytic lymphoma, burkitt's lymphoma, multiple myeloma, leukemias (chronic lymphocytic leukemia, perpetual granulocytic leukemia) (it is generally incapable in intense blastic emergency), intense myelogenous and monocytic leukemia, intense lymphoblastic (immature microorganism) leukemia in youngsters (cyclophosphamide given amid abatement is compelling in drawing out its term), mycosis fungoides (progressed disease), neuroblastoma (spread disease), adenocarcinoma of the ovary, retinoblastoma, carcinoma of the bosom.
Oral cyclophosphamide dosing is more often than not in the scope of 1 to 5 mg/kg/day for both introductory and upkeep dosing.
It 's stockpiling ought to be at or beneath 25oC (77oF) is prescribed; this item will withstand brief introduction to temperatures up to 30°c (86°f) however ought to be shielded from temperatures over 30oC (86oF).
Stomach related system
Vomiting and spewing regularly happen with cyclophosphamide treatment. Anorexia and, less habitually, stomach distress or torment and the runs may happen. There are segregated reports of hemorrhagic colitis, oral mucosal ulceration and jaundice happening amid treatment. These antagonistic medication impacts for the most part transmit when cyclophosphamide treatment is ceased.
Skin and its structures
Alopecia happens regularly in patients treated with cyclophosphamide. The hair can be relied upon to develop back after treatment with the medication or notwithstanding amid proceeded with sedate treatment, however it might be diverse in surface or shading. Skin rash happens once in a while in patients getting the medication. Pigmentation of the skin and changes in nails can happen. Extremely uncommon reports of stevens-johnson disorder and lethal epidermal necrolysis have been gotten amid postmarketing observation; because of the idea of unconstrained antagonistic occasion detailing, a complete causal relationship to cyclophosphamide has not been set up.
Leukopenia happens in patients treated with cyclophosphamide, is identified with the measurement of medication, and can be utilized as a dose control. Leukopenia of under 2000 cells/mm3 grows normally in patients treated with an underlying stacking do
Endoxan - Cyclophosphamide 50mg Tablet:-
|Brand Name:||Endoxan 50mg |
|Generic Name:||Cyclophosphamide 50mg Tablet|
|Contents:||Cyclophosphamide 50mg Tablet|
|Manufacturer||Zydus Biogen ( Baxter) |
|Also Known As: ||Cytoxan, Neosar, Procytox, Revimmune|
|Packing:||Price Per Tablet|