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Mitoxantrone is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. Mitoxantrone is classified as an "antitumor antibiotic." (For more detail, see "How Mitoxantrone Works" section below).
What Mitoxantrone Is Used For:
Advanced prostate cancer not responding to hormone treatment - used in combination with steroids.
Acute myelogenous leukemia (AML)
severe side effects.
The following side effects are common (occurring in greater than 30%) for patients taking Mitoxantrone:
Low blood counts. Your white and red blood cells and platelets may temporarily decrease. This can put you at increased risk for infection, anemia and/or bleeding.
Nadir: Meaning low point, nadir is the point in time between chemotherapy cycles in which you experience low blood counts. Onset: 7 - 10 days
Nadir: 10 -14 days
Recovery: 21 days
Nausea and vomiting
Increases in blood tests measuring liver function. These return to normal once treatment is discontinued.