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Generic name: Imatinib Mesylate
Other names: STI-571
Gleevec is the trade name for the generic drug name Imatinib Mesylate. STI-571 is another name for Imatinib Mesylate. In some cases, health care professionals may use the trade name Gleevec or other name STI-571 when referring to the generic drug name Imatinib Mesylate.
Drug type: Gleevec is a targeted therapy. Gleevec is classified as a signal transduction inhibitor - protein-tyrosine kinase inhibitor. (For more detail, see "How this drug works" below).
What Gleevec Is Used For:
Newly diagnosed adult and pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in chronic phase.
Ph+ CML in blast crisis, accelerated phase, or chronic phase after failure of interferon-alpha therapy.
Adult patients with relapsed or refractory Philadelphia chromosome + acute lymphoblastic leukemia (Ph+ ALL).
Adult patients with myelodysplastic/myeloproliferative diseases (MDS/MPD) associated with PDGFR gene rearrangements.
Gastrointestinal stromal tumors that are C-kit positive.
Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.
How Gleevec Is Given:
Gleevec is a pill, taken by mouth, once or twice daily.
Gleevec should be taken with a large glass of water, after a meal.
The amount of Gleevec that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.