Emcyt Estramustine phosphate 140mg Capsule

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Product Code : 32

Product Description

Estramustine phosphate capsules bp 140 mg is utilized as a part of palliative treatment of metastatic or dynamic prostate growth. Estramustine seems to go about as a generally frail alkylating specialist and confers a powerless estrogenic action. The estrogenic part of the particle goes about as a transporter to encourage specific take-up of the medication into estrogen receptor-positive cells. In view of the specific steroidal take-up, the alkylating impact of the nitrogen mustard is improved in these cells. Estramustine phosphate is promptly dephosphorylated amid assimilation, and the significant metabolites in plasma are estramustine, the estrone simple, estradiol, and estrone.

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Additional information :

Dosage in prostate cancer

Adults :

14 mg/kg/day (extend, 10 to 16 mg/kg/day) in 3 to 4 partitioned dosages for 30 to 90 days preceding surveying for continuation of treatment. Proceed with treatment as long as reaction is ideal.
General advice
Control with water 1 h or more previously or 2 h after suppers.

Indications :

Hypertension; chf; edema; expanded danger of cerebrovascular mishap; mi, thrombosis.
Cns
Dormancy; enthusiastic lability; sleep deprivation.
Rash; dry skin; simple wounding.
Endocrine
Diminished glucose resistance; bosom delicacy or development.
Sickness; retching; looseness of the bowels; anorexia; fart; lifted lfts.
Genitourinary
Diminished glucose resistance; bosom delicacy; bosom development.
Hematologic
Leukopenia and thrombocytopenia have been accounted for in few patients.
Musculoskeletal
Leg spasms.
Respiratory
Dyspnea.

Emcyt (Generic) Estramustine phosphate 140mg Capsule:-

Brand Name:	X-Trant
Generic Name:	Estramustine phosphate 140mg Capsule
Contents:	Estramustine phosphate 140mg Capsule
Form:	Capsule
Manufacturer	Natco India Ltd
Strength:	140mg
Packing:	Price Per pack of 100 Capsule